Chapter6 Lecture

Chapter6 Lecture - Environmental Toxicology and Chemistry...

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Unformatted text preview: Environmental Toxicology and Chemistry Risk Analysis depends on understanding these "All things are poison and nothing is without poison, only the dose permits something not to be poisonous." Paracelsus (1493-1541) Philippus Theophrastus Aureolus Bombastus von Hohenheim s a l k a l o i d c o n t e n t , b u t t h e s e e d s a c c Toxic principle. Coniine and related pyridine-type alkaloids are present in the root, young plants and seeds. As plants mature, the foliage loses alkaloid content, but the seeds accumulate the alkaloid. Hay can retain toxicity. Toxicity. The whole green plant is toxic at dosages of approximately 1% of body weight. Socrates was put to death by way of this poison in 399 BC . History in brief Toxicology one of the oldest (practical) sciences Toxins in Nature: Plants Hemlock Snakes -Mushrooms Ciquatera Most common fish poisoning Red Tides Dinoflagellates, food web structure Volcanoes H 2 S Lakes CO 2, H 2 S, CO, CH 4 Olson Twin? She likes her Cobra Snake so much she gladly poses with/for him while attending the Chanel Cruise Collection 2007-2008 fashion show last Friday. ?Mary-Kate Cleopatra Fell on her ASP instead Copperhead bite on finger History in brief Toxicology one of the oldest (practical) sciences Toxins in Nature: Plants Hemlock Snakes Mushrooms Ciquatera Most common fish poisoning Red Tides Dinoflagellates, food web structure Volcanoes H 2 S Lakes CO 2, H 2 S, CO, CH 4 Though generally considered poisonous, Amanita muscaria is otherwise famed for its hallucinogenic properties with its main psychoactive constituent being the compound muscimol . Used as an intoxicant by the Koryaks of the Kamchatka Krai of eastern Siberia, the mushroom has had a religious significance in Siberian culture and possibly also in ancient Scandinavian culture. On April 24, 2008 scientists at Woods Hole Oceanographic Institution (WHOI) and North Carolina State University (NCSU) forecasted the potential for a larger than normal Alexandrium bloom in the Gulf of Maine. Depending on weather and ocean conditions, this years bloom could be comparable to the historic bloom of 2005 that resulted in an estimated direct impact of $18 million to the commercial shellfishing industry in Massachusetts. Alexandrium is a dinoflagellate that has two flagella that enable it to swim. One flagellum encircles the cell causing the cell to rotate and move forward, while the other extends behind the cell and controls the direction. Some kinds of Alexandrium occur in chains that, when seen through a microscope, look like small trains moving in the water. Some Alexandrium species produce toxins that cause Paralytic Shellfish Poisoning. This is what most people in Washington mean when they talk about red tides....
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Chapter6 Lecture - Environmental Toxicology and Chemistry...

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