Lesson 14-15 Gene Mutation and DNA Repair.ppt

Lesson 14-15 Gene Mutation and DNA Repair.ppt - BIO 325...

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Unformatted text preview: BIO 325 Genetics Lectures 14 and 15 Gene Mutation and DNA Repair Anyone can hold the helm when the sea is calm. Publilius Syrus Gene Mutation and DNA Repair A mutation is a heritable change in the genetic material. Gene Mutation and DNA Repair A mutation is a heritable change in the genetic material. Chromosome mutations are changes in chromosome structure. Gene Mutation and DNA Repair A mutation is a heritable change in the genetic material. Chromosome mutations are changes in chromosome structure. Genome mutations are changes in chromosome number. Gene Mutation and DNA Repair A mutation is a heritable change in the genetic material. Chromosome mutations are changes in chromosome structure. Genome mutations are changes in chromosome number. Single-gene mutations are relatively small changes in chromosome structure that occur within a particular gene. Gene Mutation and DNA Repair Gene mutations are molecular changes in the DNA sequence of a gene. Consequences of Mutation Gene mutations are molecular changes in the DNA sequence of a gene. A gene mutation represents a permanent change in the DNA sequence. Consequences of Mutation Consequences of Mutation Point mutations change a single base within the DNA. Consequences of Mutation Point mutations change a single base within the DNA. Base substitutions involve a change from one base to another. Consequences of Mutation Point mutations change a single base within the DNA. Base substitutions involve a change from one base to another. 5 AACGC T AGATC 3 3 TTGCG A TCTAG 5 5 AACGC G AGATC 3 3 TTGCG C TCTAG 5 Transitions involve a change from a pyrimidine to another pyrimidine (e.g., T to C) or a purine to another purine (e.g., A to G). Consequences of Mutation Point mutations change a single base within the DNA. Base substitutions involve a change from one base to another. 5 AACGC T AGATC 3 3 TTGCG A TCTAG 5 5 AACGC G AGATC 3 3 TTGCG C TCTAG 5 Transitions involve a change from a pyrimidine to another pyrimidine (e.g., T to C) or a purine to another purine (e.g., A to G). Transversions involve a change from a pyrimidine to a purine, or vice-versa. Consequences of Mutation Point mutations change a single base within the DNA. Base substitutions involve a change from one base to another. 5 AACGC T AGATC 3 3 TTGCG A TCTAG 5 5 AACGC G AGATC 3 3 TTGCG C TCTAG 5 Besides base substitutions, a single base pair or multiple base pairs may be deleted from the DNA . . . Consequences of Mutation Besides base substitutions, a single base pair or multiple base pairs may be deleted from the DNA . . . Consequences of Mutation 5 AACGC T AGATC 3 3 TTGCG A TCTAG 5 5 AACGCAGATC 3 3 TTGCGTCTAG 5 5 AACGC TAG ATC 3 3 TTGCG ATC TAG 5 5 AACGCATC 3 3 TTGCGTAG 5 Besides base substitutions, a single base pair or multiple base pairs may be deleted from the DNA . . ....
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This note was uploaded on 02/27/2011 for the course BIO 325 taught by Professor Saxena during the Fall '08 term at University of Texas at Austin.

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Lesson 14-15 Gene Mutation and DNA Repair.ppt - BIO 325...

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