lec7.2011.handout - Lecture 7 How small GTPases control...

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Lecture 7 How small GTPases control where coat proteins assemble Traffic from the ER to the Golgi What happens to proteins in these compartments? How do proteins travel between compartments?
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Vesicle Fusion:  How does a vesicle fuse with its appropriate target  membrane?
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The SNARE Complex: t-snare + v-snare 13-16
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T-S na re /V-s na re  C o m ple xe s  Are  s o  S ta b le  Tha t Ene rg y is  Re q uire d to  Pry The m  Apa rt  13-18
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Ra b  Pro te ins  a nd The ir “Effe c to rs ” Als o   Pro vide  S pe c ific ity to   Ve s ic le  Ta rg e ting     * At ho m e  re a ding
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Vesicle Fusion:  How does a vesicle fuse with its appropriate target  membrane?
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How COPII vesicles bud from the ER Coat for vesicle from ER= COP II subunits + SAR1, a small GTP protein Vesicle Budding : 1. Coat proteins bind to signal sequences in cytoplasmic tail of IMP (Integral Membrane Protein) 2. The luminal side of the IMP binds the soluble cargo. Alberts 13-13
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What does SAR1p, the small GTPase DO? When in the GTP-bound state
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This note was uploaded on 02/27/2011 for the course BIO 320 taught by Professor Staff during the Spring '08 term at University of Texas at Austin.

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lec7.2011.handout - Lecture 7 How small GTPases control...

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