Lect3_2011slides - Lecture 3 Protein Folding, Degradation &...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Lecture 3 Protein Folding, Degradation ***OPTIONAL READING: review articles*** Scienti±c American 284 :68-73. Ubiquitin in Endocytosis and Signaling. Science 325:201-205 Polyubiquitin Chains Speci±city and Processivity. ACS Chem. Biol. 1:20-24 Downloadable @ blackboard The folding of a protein is controlled by its amino acid sequence Alberts, 3-5 •Some proteins fold on their own •Most proteins need help to fold Few proteins can refold after complete denaturation. Alberts, 3-6 Most proteins begin to fold as they are synthesized Alberts, 6-84 The interior of a cell is a very crowded space! David Goodsell ʼ s Cell Art http://mgl.scripps.edu/people/goodsell/illustration/patterson Cells have special proteins called Chaperones to help the correct folding of proteins. Some Chaperones are highly specialized to their
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 02/27/2011 for the course BIO 320 taught by Professor Staff during the Spring '08 term at University of Texas at Austin.

Page1 / 4

Lect3_2011slides - Lecture 3 Protein Folding, Degradation &...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online