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Unformatted text preview: BIO 106 2009 Professor Owen 10/7/2009 14 - DNA Structure & Function 1 DNA Structure & Function DNA Structure & Function Chromosomes Contain Genes Chromosomes Contain Genes ECB 3 5-1 The genetic material is organized in chromosomes, which are visible only when the cell is dividing. Chromosomes contain DNA and protein. How do we know How do we know genes are made of genes are made of DNA? DNA? Griffiths experiment: 1920s: are genes protein or DNA? What transformed What transformed the bacteria? the bacteria? ECB 3 5-3 Heat-killed lethal bacteria transformed the living non-lethal bacteria (R) into the lethal strain (S). Averys Averys Experiment Experiment Avery, MacLeod, and McCarthy demonstrated that DNA is the genetic material that transformed Griffiths ECB 3 5-4 transformed Griffith s bacteria. Biology Project (http://www.biology.arizona.edu/) This is a good example of how one good experiment can lead other researchers. What is DNA? What is DNA? Watson & Crick (and Watson & Crick (and Wilkins & Franklin) in Wilkins & Franklin) in 1953 described the 1953 described the model for the structure model for the structure of DNA. of DNA. Talk to your neighbor: What is DNA made of? A. deoxyribose sugars paired with nucleotide bases B. two deoxyribose sugar backbones linked together with nucleotide bases together with nucleotide bases C. two deoxyribose sugar-phosphate backbones linked together with nucleotide bases...
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