Exam%204%20Bios%20100%20fall%202009

Exam%204%20Bios%20100%20fall%202009 - Bios 100 Fall 2009 1....

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Bios 100 Fall 2009 Exam 4 1. Transcription begins at a promotor. What is a promotor? A. part of the RNA molecule itself B. a transcribed sequence of DNA C. a site found on the RNA polymerase D. a site in DNA where RNA polymerase will bind E. part of the small subunit of a ribosome 2. What determines which base is to be added to an RNA strand during transcription? A. The order of the chemical groups in the backbone of the RNA molecule B. Base pairing between the two DNA strands C. Base pairing between the DNA template strand and the RNA nucleotides D. The previous base E. The three triplets before the area being transcribed. 3. Which of the following terms best describes the relationship between the newly synthesized RNA molecule and the DNA template strand? A. Permanently base-paired B. Identical C. Complementary D. Covalently bound E. Mutated 4. What happens to RNA polymerase II after it has completed transcription of a gene? A. It is degraded. B. It is free to bind to another promoter and begin transcription. C. It begins transcribing the next gene on the chromosome. D. It joins with another RNA polymerase to carry out transcription. E. It immediately binds to a small subunit of RNA polymerase III. 5. An exon is A. The protein that initiates transcription B. The protein that initiates translation C. That portion of the DNA that will be spliced out D. The part of DNA that will be incorporated into the mature mRNA E. The small portion of the ribosome needed to make protein
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6. The anti-codon portion of the tRNA A. Binds to the amino acid being transferred B. Is essential in forming the alpha helix structure of tRNA C. Associates with the complementary base pairs on mRNA D. Was found to be radioactively labeled by researchers using cell-free preparations to examine protein synthesis E. Binds to the ribosome to ensure translation begins at the correct location. 7. α -amanitin was found to be very potent in A. inhibiting RNA polymerase II B. preventing translation of large proteins C. enhancing the production of mature mRNA strands D. inhibiting the function of the spliceosome E. promoting the division of cells and increasing the rate of the cell cycle Use the answer key below for the following four questions; use the phrases that best describe what has occurred. A. There has been no mutation. B. A silent mutation has occurred C. A missense mutation has occurred D. A nonsense mutation has occurred E. A frameshift mutation has occurred 8. An alteration in a person’s DNA results in a change in the original DNA sequence from TATTGC to TACTGC. The original sequence codes for tyrosine-tryptophan. The altered sequence also codes for tyrosine -tryptophan. 9. An alteration in a person’s DNA results in a change in the original DNA sequence from TATTGC to TATTGA. The original sequence codes for tyrosine-tryptophan; the altered sequence codes for a tyrosine followed by a STOP. 10. An alteration in a person’s DNA results in a change in the original
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Exam%204%20Bios%20100%20fall%202009 - Bios 100 Fall 2009 1....

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