1Day 14Glycolysis and FermentationHarvesting energyWithout an external electron acceptorToday’s Topics1. Glycolysis: An example of a redox reaction that powers cells2.Fermentation: recycling NADH back to NAD+ in the absence of an external electron acceptor3.Using ATP in biosynthesisAll life is aboutObtaining electrons from some donor,Transferring the electrons to an acceptorAnd exploiting the released energy. 1) Where to get electrons? That is, what to use as a donor2) What to do with the electrons afterwards? Or, what to use as an acceptorLife has found many solutions.Since all forms of life are run by REDOX chemistry, two problems must be solved in some way:1. The donor is some organic molecule or “food”(heterotrophslike you and me)2. The ultimate acceptor comes from inside the cell(fermenters) (animal cells sometimes do this)Today we’ll talk about life forms in which:General diagram of how cells burn fuel (so far)Fuel ABCDEF2e-, 2H+2e-, 2H+GReleaseenergyReleaseenergyNADHNADHpullpushBy adjusting concentrationsvia highly exergonic Redox Reaction
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