Chapter 19

Chapter 19 - C hapter 19: Cell adhesion 4 main functions:...

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Chapter 19: Cell adhesion 4 main functions: - Anchoring junctions including both cell-cell adhesions and cell-matrix adhesions transmit stresses and are tethered to CS filaments inside the cell - Occluding junction seal the gaps between cells in epithelia so as to make the sheet impermeable - Channel forming junctions create passageways linking cytoplasms of adjacent cells - Signal relaying junctions allow signals to be relayed from cell t cell across the PM @ target sites Cadherins and cell-cell adhesion - Adheren junctions are anchoprage sites for actin filaments - Desmosomes junctions are anchorage sites for intermediate filaments - TM adhesion proteins span the membrane with one end linking to the CS inside the cell and the other end linking to other structures outside it o Cadherin: mediate attachment cell to cell ( adheren junctions) o Integrin: mediate attachment cell to matrix (desmosomes junctions) Cadherins mediate CA dependent cellcell adhesion in all animals - Removal of CA from the extracellular matrix causes adhesions to come drift
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This note was uploaded on 03/08/2011 for the course BIO 110 taught by Professor Rexach during the Spring '08 term at UCSC.

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Chapter 19 - C hapter 19: Cell adhesion 4 main functions:...

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