IB 117 _13 Perph NS Analgesics

IB 117 _13 Perph NS Analgesics - to glucocorticoids...

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IB 117 Thomas Carlson Peripheral nervous system analgesics & anti-inflammatories Plant origin Geographic origins Mechanism of action cocaine and derivatives procaine, tetracaine, & lidocaine Erythroxylum coca South American Andes Mtns Local blockade of nerve impulses acetylsalicylic acid, salicylic acid, Filipendula ulmaria Europe Inhibits cyclooxygenase which inhibits prostaglandin synthesis salicin, saligenin Salix alba Europe Inhibits cyclooxygenase which inhibits prostaglandin synthesis diosgenin as precursor
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Unformatted text preview: to glucocorticoids Dioscorea mexicana Mexico Blocks cytokine production. Inhibits phospholipids conversion to arachidonic acid which inhibits prostaglandin synthesis hydroxychloroquine Cinchona officinalis South America anti-inflammatory to treat rheumatoid arthritis harpagoside Harpagophytum procumbens Southern Africa anti-inflammatory to treat lower back pain, hip pain, and knee pain capsaicin Capsicum annuum & Capsicum frutescens Tropical America Agonist at capsaicin receptor, a heat-activated ion channel pain pathway...
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