IB 117 _19 CV CHF _ arrhythmias

IB 117 _19 CV CHF _ arrhythmias - glycosides Nerium...

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IB 117 Thomas Carlson Cardiovascular remedies CHF & arrhythmias Plant origin Geographical origin Mechanism of action / therapeutic uses digoxin Digitalis lanata Europe Inhibition of α subunit of Na + ,K + -ATPase causing increase in cytosolic Ca+ to tx CHF digitoxin Digitalis purpurea Europe Inhibition of α subunit of Na + ,K + -ATPase causing increase in cytosolic Ca+ to tx CHF ouabain Strophanthus gratus Africa Inhibition of α subunit of Na + ,K + -ATPase causing increase in cytosolic Ca+ to tx CHF cardiac
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Unformatted text preview: glycosides Nerium oleander Mediterranean increases cytosolic Ca+ to tx CHF lidocaine, procainamide, tocainide Erythroxylum coca South America block cardiac Na+ channels to slow conduction and treat tachyarrhythmias verapamil derived from papaverine Papaver somniferum SE Europe block cardiac Ca+ channels to slow conduction and treat tachyarrhythmias quinidine Cinchona officinalis South America atropine Atropa belladonna Europe blocks cholinergic receptors to treat bradycardia...
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