IB 117 _22 Cancer - Hodgkins and non-Hodgkins lymphomas...

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IB 117 Thomas Carlson Cancer remedies Plant origin Geographic origin Mechanism of action / therapeutic uses colchicum colchicine Colchicum autumnale Europe Disorganizes spindle mechanism at mitosis and treats tumors and gout etoposide, teniposide Podophyllum peltatum & P. hexandrum Eastern North America, Himalayas Blocks G1 phase of mitosis and tx testicular CA, Hodgkin’s and non- Hodgkin’s lymphomas podophyllum resin from rhizome, podophyllotoxin Podophyllum peltatum & P. hexandrum Eastern North America, Himalayas Binds microtubules causing mitotic arrest in metaphase to tx condylomata acuminata vincristine, vinblastine Catharanthus roseus Madagascar Binds protein tubulin causing mitotic arrest in metaphase to tx acute childhood leukemia,
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Unformatted text preview: Hodgkins and non-Hodgkins lymphomas paclitaxel (taxol), docetaxel (taxotere) Taxus brevifolia NW North America antimicrotubule & antimitotic to tx metastatic ovarian and breast cancer European mistletoe Viscum album Europe Tx breast cancer and joint inflammation lycopene Solanum esculenta South America Antioxidant reduces risk of developing prostate CA phytochemicals in fruits and vegetables Reduces risk of developing cancer isoflavones, genistein Glycine max China Binds weakly to type II estrogen binding sites and outcompetes stronger estrogens resulting in a reduction in receptor stimulation and reduces risk for breast, uterine, and prostate cancers lignans in seed wall Linum usitatissimum Europe Reduces risk for breast cancer...
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This note was uploaded on 03/09/2011 for the course IB 117 taught by Professor Professorcarlson during the Spring '08 term at University of California, Berkeley.

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