MCB+102+F10+Lect+ 12 +POST

MCB+102+F10+Lect+ 12 +POST - A biomembrane demarcates the...

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Lysosome Secretory vesicles Endoplasmic reticulum Peroxisome Plasma membrane A biomembrane demarcates the cell boundary and delimits each organelle compartment Every biomembrane has a unique composition that is required for its function Every biomembrane is a lipid bilayer outside inside
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•Compartmentation •Selective exchange •Active transport •Association & communication with, and response to, the extracellular environment milieu and other cells •Scaffold for biochemical activities (including energy transduction, signal transduction, lipid biosynthesis, etc.) Some Functions of Biomembranes
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Common Properties of Biomembranes •Continuous closed sheet-like structure only 2 molecules thick. •Composed of ~50% lipids and ~50% proteins, including also glycolipids, lipoproteins and glycoproteins, assembled non-covalently. •Membrane lipids are all small, markedly amphipathic molecules with a strong propensity to spontaneusly self-associate, thereby forming closed compartments. •Biomembranes act as a barrier to the free passage of polar molecules, especially ions, establishing a transmembrane electrochemical potential. •Biomembranes are asymmetric because the composition and orientation of the proteins, and the composition of the lipids, in the two leaflets is distinct. The distinctive function of each biomembrane is dictated by the
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MCB+102+F10+Lect+ 12 +POST - A biomembrane demarcates the...

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