# Handout 1 - TA Anna Gruzman E-mail [email protected] 1 a...

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TA: Anna Gruzman Section 1 E-mail: [email protected] 12/10/10 1. a. Write out the Nernst equation and explain what each variable means. b. What does the Nernst equation tell you? c. Fill in the values for the following table: (It would be a good idea to memorize/ understand this for the exams) Conc. Inside Cell Conc. Outside Cell Down Gradient Flow Effect on Membrane Potential K+ 3.5-5 mmol Na+ 140 mmol Cl- 5-10 mmol Ca++ 1 mmol d. Fill in the following table [Ion]in: (mM) [Ion]out: (mM) Eion: (mV) Driving force (mv): Vm= - 70 mV Driving force (mV) Vm = + 100 mv Direction Vm= -70 Direction Vm = + 100 K= 150 1.5 Na= 14 140 Cl = 100 10 Ca= 0.0001 1 Brief Review of Logs: (Can look at this later if it’s been a while since you did math) - If log( base 10) X = a then 10^a = x - This means that….. o Log (1/100) = - 2 o Log (100) = 2 o Log ( 1/10) = -1 o Usually on the exam you will get numbers that are fairly easy to do logs with…if you are worried about wasting time thinking about this it may be a good idea to just go ahead and memorize the common ones Finding the Driving Force:

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• Fall '07
• French
• Driving Force, GHK- Goldman Hodgkin Katz

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