23.Trans.Infl.Tox.11

23.Trans.Infl.Tox.11 - Special Topic: How Transformations...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Special Topic: How Transformations Influence Toxicity Introduction Some Processes in Vascular Plants Some Processes in Vertebrates Summary and Conclusions
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
I. Introduction Reactions often directly detoxify a chemical. Reactions almost always increase water solubility of a chemical. However, chemicals may be instead activated. Differences in toxicity are often traced to differences in biodegradation.
Background image of page 2
II. Some Processes in Vascular Plants Monuron, a substituted urea class herbicide, is used in cotton fields and on other crops. Cotton is selectively resistant via P450- catalyzed N -demethylation (oxidation).
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Some Processes in Vascular Plants Propanil, an acetanilide herbicide, is commonly used for weed control on many crops, including rice, potatoes and wheat. Most crops are selectively resistant via amidase-catalyzed hydrolysis. The weeds are often not!
Background image of page 4
Atrazine, a triazine herbicide, is commonly used in for weed control in corn fields. Corn is selectively resistant via GST-catalyzed glutathione conjugation (Cl is the leaving group). Many weeds are
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 03/10/2011 for the course ETX 102A taught by Professor Ronaldtjeerdema during the Winter '10 term at UC Davis.

Page1 / 20

23.Trans.Infl.Tox.11 - Special Topic: How Transformations...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online