8.Part.Bioaccum.11

8.Part.Bioaccum.11 - Partitioning and Bioaccumulation...

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Partitioning and Bioaccumulation Organic Phase Partitioning Risk, Exposure and Dose Bioaccumulation Absorption, Disposition, Depuration Kinetic Modeling Summary and Conclusions
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I. Organic Phase Partitioning Octanol-water coefficient estimates the partitioning of a chemical between aqueous and organic phases. Concentrations will probably be different but the fugacity value is equal Octanol serves as a model for organics (soil carbon or adipose tissues). ow
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K ow is Inversely Proportional to Solubility
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K ow Estimates “Organic” Solubility Neutral organics are much more soluble in organic phases. Neutral organics are generally more fat soluble with increasing molecular mass. In the environment large neutral organics tend to be associated with the organic carbon fraction of soils and the adipose tissues of organisms.
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Risk is the probability that a chemical exposure will cause a toxic effect. Chemical risk = exposure x potency Risk is a function of both potency and exposure. Exposure represents the
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This note was uploaded on 03/10/2011 for the course ETX 102A taught by Professor Ronaldtjeerdema during the Winter '10 term at UC Davis.

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8.Part.Bioaccum.11 - Partitioning and Bioaccumulation...

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