Lecture_chapter9_Show - DNA Structure and Function Chapter...

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DNA Structure and Function Chapter 9
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Clones Nuclear transfer from adult cell Structural and functional problems Most adult DNA inactive Potential benefits Replacement organs Endangered animals
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Impacts, Issues Video Goodbye Dolly
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Miescher Discovered DNA 1868 Johann Miescher investigated chemical composition of nucleus Isolated organic acid high in phosphorus He called it nuclein We call it DNA (deoxyribonucleic acid)
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Griffith Discovers Transformation 1928 Attempting to develop a vaccine Isolated two strains of Streptococcus pneumoniae Rough strain was harmless Smooth strain was pathogenic
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Griffith Discovers Transformation 1. Mice injected with live cells of harmless strain R 2. Mice injected with live cells of killer strain S 3. Mice injected with heat-killed S cells 4. Mice injected with live R cells plus heat-killed S cells Mice die. Live S cells in their blood Mice live. No live R cells in their blood Mice die. Live S cells in their blood Mice live. No live S cells in their blood
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Transformation Harmless R cells were transformed by material from dead S cells Descendents of transformed cells were also pathogenic
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What Is the Transforming Material? Avery found protein-digesting enzymes
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Lecture_chapter9_Show - DNA Structure and Function Chapter...

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