Tetrahydro-β-Carboline

Tetrahydro-β-Carboline - Patricia Mora...

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Patricia Mora Chem 3BL Synthesis of 1,2,3,4 Tetrahydro-β-Carboline The purpose of this lab is to synthesize 1, 2, 3, 4 Tetrahydro-β-Carboline from tryptamine and glyoxylic acid. The reaction involved the condensation of tryptamine with glyoxylic acid, creating an imine intermediate. The result of the reaction is a carbon-carbon bond that leads to decarboxylation of the carbonyl group. Carbon dioxide is formed after potassium hydroxide deprotonates the carboxylic acid of glyoxylic acid. My percent yield from this experiment was 12.8%. Factors that could have contributed to
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