PS_5_older

PS_5_older - Bio 115 Problem set #5 February 11, 2005 1. In...

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Bio 115 February 11, 2005 Problem set #5 1. In group I introns, why is a guanosine cofactor required for the first chemical step of splicing but not the second? 2. Considering group I, group II and pre-mRNA introns, describe where energetic inputs are required to drive the splicing process. 3. What feature of RNA makes it ideal for performing chemical reactions? 4. Rank DNA, RNA and proteins in terms of: a. the amount of genetic information that they carry b. their ability to form complex structures 5. Briefly, what is the "RNA world" hypothesis? 6. In group one introns, what function does the "internal guide sequence" perform? How is this function carried out in pre-mRNA splicing? 7. In terms of the fundamental mechanisms by which splicing occurs, how does tRNA splicing differ from splicing of group I, group II and pre-mRNA splicing? 8. What enzymatic activity does RNAseH possess?
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9. Some group I introns require proteins. called maturases, in order to splice. What is the function of a maturase? 10.
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PS_5_older - Bio 115 Problem set #5 February 11, 2005 1. In...

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