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5_Cardio_Blood%20Ch%2019 - Chapter 19 Cardiovascular System...

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19-1 Chapter 19 Cardiovascular System: Blood
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Cardiovascular system Blood is a major component Functions? Composed of The Heart Blood vessels BLOOD
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Characteristics of Blood Blood = what type of tissue? Composed of a variety of cells and their extracellular matrix 37-54% Formed elements 46-63% Liquid medium =
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19-4 Composition of Blood
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1/30/07
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Plasma Contains mostly water (92%) Electrolytes and proteins (7%) “Free-floating stuff” Proteins Always remain in the plasma – give viscous consistency 3 main plasma proteins
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Plasma Albumins Functions? Globulins Functions? Fibrinogen Functions? Blood tests: Plasma vs. Serum Serum = Thus what has been removed but also removes
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19-9
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19-10
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Formed Elements Red Blood Cells = Erythrocytes (RBCs) Function of RBC’s Transports O 2 from tissue to lungs Transports CO 2 from cells/tissue to lungs Structure Saucer-shaped cell = biconcave disk Special features Lack of these organelles is advantageous to function No nucleus = no cell division = Cell can assume biconcave shape – how is that an advantage?
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19-12 Red Blood Cells Found in higher concentration in male than in female plasma Components 1/3 Hemoglobin 2/3 Lipids, ATP, carbonic anhydrase
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Formed Elements: RBC’s Importance of Shape to function (review in text) No mitochondria – O 2 necessary for ATP production – If present, the O 2 will be consumed Also gives more space in the cell
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Molecular content of RBC’s Stocked with Hemoglobin (Hb) Protein Makes up 95% of all intracellular proteins There are approx. 280 million molecules of Hb in each RBC Normal range in grams per mL whole blood = g/dl ? Hb = protein with 4 pieces (subunits ) 4 polypeptide chains = Types?
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Molecular content of RBC’s With each globin there is a heme group Special chemical compound containing Fe 2+ Fe 2+ of globin binds to ? Blood leaving lungs is rich in O 2 – Fe- O 2 = bright red in color Blood going to lungs containing CO 2 = dark red in color
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Molecular content of RBC’s RBC’s contain a special enzyme Carbonic Anhydrase Helps in CO 2 transport in the blood – (later)
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Formed Elements: White Blood Cells White Blood Cells = Leukocytes Approx. 0.1% of blood total Come in many shapes and forms Granular (3 types) Agranular (2 types) Common Features
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Specific targets of each type of WBC’s Functions: Clean Up & Defense
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