Practice_Final _key_2011 - B iocl00B Winter 20ll Rubin 1)...

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Biocl00B Winter 20ll Rubin 1) lmagine you have a metrod that determines how much compound enteE a bacterial cell so that vou courd essenriarv measure uptarJ .aGs iffiortionartoh";;";;;;ih; ftmorane;. You measure the bllorving rates for two cornpounds: a) la/hich compound "*"*j:- Tl1_tloust 11edj+"d difrrsion and which enrrers rhe cetl through passive diftrsion? Expnrn your ansner. [g pts] C-^1r. ..,oJ -b C(/tLo^+1*f"r /.... ".- \Ji-U /l .l *)f I F- tn) L^R$ +L ovel o")) ..'l- o? 4' ll {,sl* ;/ ;s ),At -H-l n onl,'> +1"1. rvu):otd )..il,t:,n. 0 o-nl,s )4*1\ f^ss:w ):il"s'^' l,r l/_ CB) Lr J.ft.,l,,. .. rJ*s ll-l Ve r;J\.r<- "'e tL f^le o{ &^frrvnJ
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Biocl00B Winter 20ll Rubin b) Suppose you determine that the compound that enters through mediated difrtsion is glutamine, and you leam that this bacGria has a channel that facilitates glutamine diffrrsion. You find that the diftrsion of both asparagine and homoglutamine (like glutamine but extra methylene in the sidechain) are not enhances by the channel. Discuss what struc{ural features of the channel and its mechanism of facilitating dift.rsion may explain the difierences in behavior of these molecules. [10 pts] .sl 6t^ 1,*nc 4v -C-c -o' )l gQu It '- t c---t) \ rv$u A<^ ,r | 'il to fifN - C- O-c ) .JJ, I Czo I ,r4 l-. .- rl" AOrlt u ff.vt !- 1! o' vt) cHt '. U. L tl. .- I -.,
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This note was uploaded on 03/16/2011 for the course BIOC 100B taught by Professor Sethrubin during the Winter '10 term at University of California, Santa Cruz.

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Practice_Final _key_2011 - B iocl00B Winter 20ll Rubin 1)...

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