Blood_&_Immunity_4_1pageperslide

Blood_&_Immunity_4_1pageperslide - Blood and...

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Lecture outline: Specific Immunity Differentiation of B and T Lymphocytes Features of the Specific Immune Response B Lymphocyte Responses T Lymphocyte Responses Blood and Immunity 4
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Specific Defenses: Immune Responses Specific Immune Responses include: – Humoral immunity B cell mediated – Cell-mediated immunity T cell mediated
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Myeloid stem cells Lymphiod Stem Cells Peripheral Lymphiod Tissue Thymus T Cells B Cells ANTIBODY-MEDIATED IMMUNE RESPONSE CELL MEDIATED IMMUNE RESPONSE T Cells B Cells RBC granulocytes platelets monocyte Foreign antigen - EFFECTOR CELLS (Cytoxic ) - REGULATORY CELLS - (Helper T and Supressor cells THYMOSIN Hematopoietic Stem Cells
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Four Features of Specific Immune Response – Specificity –D i v
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Specificity Antigens: • Confer specificity • Complex proteins and polysaccharides • Part of the Foreign or self antigens – Foreign (components of bacteria, pollen, animal hair, certain drugs and food, transplanted tissue) – Self (beneficial or harmful - autoimmune diseases e.g. myastenia gravis, rheumatoid arthritis)
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Specificity • Epitopes = recognition sites for B or T cells • B cell and T cell specificity • Antigen receptors recognize certain antigens only • B cells – membrane antibodies • T cells – T cell receptors
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Antibody Structure
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This note was uploaded on 03/17/2011 for the course PSL 200 taught by Professor Averback during the Fall '11 term at University of Toronto- Toronto.

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Blood_&_Immunity_4_1pageperslide - Blood and...

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