2010-PSL-200-201--Cardio-06of07

2010-PSL-200-201--Cardio-06of07 - Cardiovascular Physiology...

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1 Cardiovascular Cardiovascular Physiology 6/7 Physiology 6/7 Department of Physiology Department of Physiology Nohjin Nohjin Kee Kee , Ph.D. Email: nohjin.kee@utoronto.ca Chapter 13
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2 The Mean Arterial Pressure ean Arterial Pressure Determinants of Mean Arterial Pressure n CO n TPR Factors Affecting Central Venous Pressure n The Skeletal Muscle Pump n The Respiratory Pump n Blood Volume n Venomotor Tone Factors Affecting The Flow of Fluid Across Capillary Walls n Filtration n Absorbtion The Lymphatic System
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3 The average aortic pressure occurring during the cardiac cycle Heart Rate Stroke Volume Total Peripheral Resistance (TPR) n In systemic circuit, the combined resistance of all the organs, including the blood vessels leading toward and away from them Determinants of Mean Arterial Pressure (MAP=COXTPR) ean Arterial Pressure
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4 Changes in Cardiac Output – Effect on the MAP hanges in Cardiac Output
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5 Changes in Cardiac Output – Effect on the MAP hanges in Cardiac Output
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6 Review - MAP The increase in CO (CO=HRXSV) leads to increase in MAP The increase in Total Peripheral Resistance (TPR) leads to increase in MAP eview
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7 Central Venous Pressure and Blood Flow to Organs Factors Affecting Central Venous Pressure n The Skeletal Muscle Pump n The Respiratory Pump n Blood Volume n Venomotor Tone Factors Affecting The Flow of Fluid Across Capillary Walls The Lymphatic System entral Venous Pressure
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8 Central Venous Pressure Venous Pressure: n Average venous pressure within the venous compartment CVP: n Pressure in the thoracic vena cava (near right atrium) entral Venous Pressure
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2010-PSL-200-201--Cardio-06of07 - Cardiovascular Physiology...

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