2010-PSL-200-201--Cardio-05of07

2010-PSL-200-201--Cardio-05of07 - Cardiovascular Physiology...

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1 Cardiovascular Physiology 5/7 Department of Physiology Nohjin Nohjin Kee Kee , Ph.D. Email: nohjin.kee@utoronto.ca Chapter 13
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2 The Blood Vessels Arteries Arterioles Capillaries Veins Patterns Of Blood Flow Within The Cardiovascular System Series Flow Parallel Flow Physical Laws Governing Blood Flow And Blood Pressure Pressure Gradient Resistance Blood Flow
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3 Arteries Veins Capillaries lood Vessels Blood Vessels
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4 lood Vessels Blood Vessels
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5 lood Vessels Blood Vessels
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6 Conduct blood from the heart to the tissues Large diameters Thick walls Stiff and flexible Act as Pressure Reservoirs Low compliance (able to expand when the pressure within them rises) lood Vessels rteries Blood Vessels - Arteries
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7 The change in volume per unit change in distending pressure Compliance = V/ (P inside –P outside ) ompliance Compliance
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8 The change in volume per unit change in distending pressure Compliance = V/ (P inside –P outside ) DP Distending Pressure V 0 A B ompliance Compliance
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9 lood Vessels Blood Vessels - Characteristics
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10 Conduct blood from small arteries to capillaries Invisible to the naked eye (part of body’s microcirculation) Serve as points of control for regulating the flow of blood through the capillary beds downstream from them Blood flow is regulated in arterioles by the contraction or relaxation of circular smooth muscles, (present in vessel walls) Contractile activity of arteriolar smooth muscle is regulated by autonomic NS and by local chemical agents and hormones n Contraction of circular SM cells arterioles to constrict →↓ blood flow through the capillaries dowstream n Relaxation of these smooth muscle cells arteriolar dilation →↑ blood flow lood Vessels rterioles Blood Vessels - Arterioles
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11 Most tissues contain metarterioles, which are structurally intermediate between arterioles and capillaries; instead of the continous layer of smooth muscle that surrounds arterioles, metarterioles possess isolated rings of smooth muscle that act as Gate Keepers at strategic points Unlike arterioles which direct blood into the interbranching vessels in a capillary bed, metarterioles serve as bypass channels or SHUNTS by directly connecting arterioles to venules lood Vessels etarterioles Blood Vessels - Metarterioles
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12 Smallest (5-10 μm) Most numerous (~ 1 billion) Thin walled (endothelium + basement membrane) Place of exchange of material between cells and blood Large surface area (6000 square meters)
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This note was uploaded on 03/17/2011 for the course PSL 200 taught by Professor Averback during the Fall '11 term at University of Toronto- Toronto.

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2010-PSL-200-201--Cardio-05of07 - Cardiovascular Physiology...

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