Lecture 09 - 020111

Lecture 09 - 020111 - 1 Lecture Julian Schroeder I. Nerve...

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Unformatted text preview: 1 Lecture Julian Schroeder I. Nerve Tissue Function and Organization II. Ion Gradients III. Resting Potential IV. Action Potential 2 I. NERVE TISSUE Function & Organization A. CELL TYPES 1) Neurons Function: carry electrical signals 2) Glial Cells and Schwann Cells Function: support, electrical insulation Figure 48.8 Input Signals dendrites Synapse • Ion Gradients: see overhead transparencies 3 II. ION GRADIENTS Figure 48.10 • Resting Potential: see: over head transparencies III. RESTING POTENTIAL Negatively charged proteins Chemical Force : K + flows out negative inside Electrical Force : opposite charges attract one another K + stops flowing out when: [chemical force] = [electrical force] Gradient (10x): equilibrium potential At 20 o C E K+ = -58 mV at room temperature at 37 o C E K+ ≈-62 mV 4 III. RESTING POTENTIAL |E K+ | ~ K + gradient (charge z = +1) E K+ = 58mV/(z) x log([K + ] out /[K + ] in ) E K+ = 58mV/(+1) x log(15mM/150mM) E K+ = 58mV x (-1) E K+ = -58mV (for 10-fold gradient)...
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This note was uploaded on 03/18/2011 for the course BILD 2 taught by Professor Schroeder during the Winter '08 term at UCSD.

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Lecture 09 - 020111 - 1 Lecture Julian Schroeder I. Nerve...

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