lecture7(2)

lecture7(2) - 9.1 Major Modes of Regulation 9.2 DNA Binding...

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Unformatted text preview: 9.1. Major Modes of Regulation 9.2. DNA Binding Proteins 9.3. Negative Control of Transcription: Repression and Induction 9.4 Positive Control of Transcription 9.5. Two-Component Regulatory Systems 9.7. Regulation of Chemotaxis Lecture 7 Lecture 7 regulation regulation : : • different conditions require different strategies • changes in nutrients available • sporulation • permits specific response • key cellular enzymes are constitutive • but impractical to make every protein all the time • excess proteins may be costly • cellular activities can be regulated at multiple levels possible mechanisms of regulation: possible mechanisms of regulation: control expression control activity feedback inhibition: feedback inhibition: • often encountered in biosynthetic pathways e.g. amino acid synthesis • “ end product inhibition ” enzyme inhibition by allosteric effector: enzyme inhibition by allosteric effector: • effector often pathway end product feedback inhibition, branched biosynthetic pathway: feedback inhibition of a common pathway: isozymes : catalyze same reaction but subject to different regulatory control enzyme modifications: enzyme modifications:...
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This note was uploaded on 03/19/2011 for the course BIOL 140 taught by Professor Dr.joshneufeld during the Spring '10 term at Waterloo.

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lecture7(2) - 9.1 Major Modes of Regulation 9.2 DNA Binding...

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