lectures_5-6

lectures_5-6 - Neurohormones and neuroendocrine control...

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Unformatted text preview: Neurohormones and neuroendocrine control guest lec dinu nesan dnesan@gmail.com The hypothalamus, pituitary, neurohormones-Hormone types, sources,function-Hyo Neurohormones: Three major groups 1. Posterior pituitary hormones synthesized in hypothalamus 2. Trophic hormones from hypothalamus that act on anterior pituitary 3. Catecholamines from adrenal medulla (modified sympathetic neurons) Fig. 7-16 The pituitary gland: called the master gland two different tissue types that merged 1. Anterior pituitary- true endocrine gland-epithelial origin-synthesize and release classic hormones 2. Posterior pituitary gland- extension of the neural tissue of the brain- secretes neurohormones made in the hypothalamus Figure 7-12 - Overview Posterior pituitary hormones: Oxytocin and vasopressin What type of hormones are oxytocin and vasopressin? They are peptide hormone since they are stored in vesicle and quick Steroid hormone are produced on deman Oxytocin: small peptide - nine amino acids ejection of milk contractions of the uterus Vasopressin (antidiuretic hormone: reudction of urine volume regulation of water): also called arginine vasopressin (AVP) small peptide - nine amino acids regulates water balance role in water retention increased osmolality increased AVP secretion Target the end tubules in the kidney Fig. 7-16 Anterior pituitary hormones under trophic hormone control Hormones of hypothalamic origin: thyrotropin-releasing hormone (TRH) gonadotropin-releasing hormone (GnRH) lsh and fsh growth hormone-releasing hormone (GHRH) GH release-inhibiting hormone (somatostatin) opposing to growth hormone corticotropin-releasing hormone (CRH) Figure 7-16 Hypothalamic-hypophyseal portal system: specialized region two sets of capillaries the advantage is direct delivery without dilution of hormone minute amount of hormone needed Hormones of the anterior pituitary: Six hormones: prolactin growth hormone (GH) gonadotropins (FSH and LH) - Sexual, secondary characteristic, germ cell adrenocorticotrophic hormone (ACTH) thyroid stimulating hormone (TSH) Prolactin= only non-trophic hormone Endocrine Control: Three Levels of Integration Figure 7-13: Hormones of the hypothalamic-anterior pituitary pathway Hypothalamic stimulation from CNS Pituitary stimulation from hypothalamic trophic Hormones Endocrine gland stimulation from pituitary trophic Hormones Endocrine Control: Three Levels of Integration Negative Feedback Controls: Long & Short Loop Reflexes Figure 7-15: Control pathway for cortisol secretion...
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lectures_5-6 - Neurohormones and neuroendocrine control...

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