Chapter 4 Notes

Chapter 4 Notes - Ingrid Shih BIO 1305-08 3 September 2010...

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Ingrid Shih BIO 1305-08 3 September 2010 Chapter 4- Nucleic Acids 1. Nucleic Acids a. Macromolecules b. Storage c. Transmission b/t generations d. Use of genetic information 2. During reproduction: DNA DNA through replication 3. Activities in the cell: DNA RNA Proteins 4. Monomer- nucleotide- sugar, phosphate group, base a. Base + Ribose/deoxy = Nucleoside + Phosphate = Nucleotide b. Uracil- RNA c. Thymine- DNA d. Pyrimidine- Cytosine (C), Thymine (T), Uracil (U) e. Purines- Adenine, Guanine (G) f. Pairing- C-G; A-T in DNA g. Pairing- C-G; A-U in RNA 5. Backbone- alternating sugars and phosphate groups 6. Nucleotides are joined by phosphodiester linkages 7. RNA- single stranded 8. DNA- double stranded (double helix) Central Dogma of Molecular Biology 1. DNA can reproduce itself exactly (replication) 2. DNA can copy its information into RNA (transcription); RNA “translates” into proteins Other Roles of Nucleotides 1. Adenosine triphosphate (ATP)- energy source 2. Guanosine triphosphate (GTP)- energy source for synthesis of proteins
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This note was uploaded on 03/23/2011 for the course BIO 1305 taught by Professor Eldridge during the Fall '08 term at Baylor.

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Chapter 4 Notes - Ingrid Shih BIO 1305-08 3 September 2010...

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