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NPB+112+11+JFA-3-10-11_SleepEEG

NPB+112+11+JFA-3-10-11_SleepEEG - CONSCIOUSNESS SLEEP and...

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CONSCIOUSNESS, SLEEP ELECTROENCEPHALOGRAPHY and ANESTHESIA Joseph Antognini, M.D. University of California, Davis CONSCIOUSNESS Normal consciousness—awareness of one’s self and one’s environment and the ability to respond to changes in these. Alertness is part of normal consciousness. Much has to happen for normal consciousness to occur Normal blood pressure and blood flow to brain Adequate oxygen and carbon dioxide levels Normal temperature, normal electrolytes, glucose No tumors or infection No seizures No drugs No trauma
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WAKEFULNESS & AWARENESS Wakefulness: Eyes open/readiness to accept stimuli: it’s objective Awareness: a subjective on-going “knowledge” of one’s environment and surroundings Memory might (or might not) be a component of these
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CONSCIOUSNESS Altered states of consciousness Drug induced Sleep Coma—unconscious and unarousable (to internal/external stimuli) Concussion Persistent vegetative state (PVS)—irregular cyclic arousal but no self-awareness Minimally Conscious State Post-ictal (post seizures) Absence seizures Akinetic mutism Locked-in syndrome Brain death
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Adapted from Koch, Laureys
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http://www.smarterdesigns.com/blog/terri.jpg A Conundrum • Are vegetative patients aware?
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Owen et al., Science 2006 Sep 8;313(5792):1402.
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