Session 14 - Life Sci 2C03 L14 Session 14 Neuron,...

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Life Sci 2C03 – L14 Session 14 – Neuron, Cytoskeleton Substances. Axoplasmic Transport and Signaling Endosome Structure of Neuron 1. Major external features of a neuron 1. Major internal features of a neuron 1. ER : protein and fat synthesis 2. Golgi Complex : make packing materials/vesicles 3. Vesicles 4. Microtubules : Axon-transport 2. Dendritic Spines 1. small projections that stud the dendrites 2. Constantly changing 3. Time-lapse imaging demonstrating changes in dendritic spines of hippocampus over minute-time scale following epileptic activity 1. Diversity: Structure-Function Relationship
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Life Sci 2C03 – L14 (E) Better designed for “associating” inputs (E) (F) Better designed for “geometric precision” and timing of activity (F) 1. Basic types of Neurons (based on projections from the cell body) Cytoskeleton Substances 1. Protein complexes that: 1. Offer shape to the neuron 2. Provide anchorage to its receptors 3. Facilitate chemical transport within it 1. Distinctive arrangement of cytoskeleton elements in neurons (LOOK AT DIAGRAM) 1. Tubulin – throughout the Neuron
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Life Sci 2C03 – L14 1. Microtubule - only in the axons
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Session 14 - Life Sci 2C03 L14 Session 14 Neuron,...

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