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Lecture 16 - 1 Glomerular Filtration Starling-Landis Forces...

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Lecture 16 Kidney III 1. Glomerular Filtration NFP =( P GC + π BC ) ( P BC + π GC ) - = - = Starling -Landis Forces involved in glomerular filtration Fig 19-9 Recall P CAP = 38mmHg for a systemic capillary P BC P GC π GC π BC (60 + 0) (15 + 29) + 16 mmHg Constrict aff. arteriole? = increase aff . resistance = decrease Net filtration pressure = increase GFR Constrict eff. arteriole? = increase eff. Resistance = Increase Net Filtration Pressure = increase GFR Balance of aff. and eff. resistances is very important in controlling GFR Level of MAP is also very important in controlling GFR Afferent arteriole Efferent arteriole P GC 3. Tubular Secretion Relatively few substances (~20) often present in great excess are actively transported into the urine from blood e.g. H + , K +, urea, ammonia, uric acid, antibiotics, PAH occurs mainly in proximial convoluted tubule, except for K + 2. Tubular Reabsorption All “valuable” substances (a very large number) are reabsorbed from the urine into the blood
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Lecture 16 - 1 Glomerular Filtration Starling-Landis Forces...

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