This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: N a m e : February 26, 2010 ETX 103A Exam II Short concise answers recommended 100 points total 1. A female smoker trying to quit applies a skin patch delivering nicotine to her blood stream by diffusion. The patch covers an area of 10 cm 2 and at steady state delivers 0.5 mg/hr to her blood stream. (20 pts) a. If nicotine has a flux of 0.01 cm/hr, what is its effective concentration in the patch? b. Assuming that nicotine has a volume of distribution (Vd) of 100 liters, that her blood concentration is 20 g/liter and her body mass is 50 kg, what is her body burden of nicotine at steady state? c. Assuming first order kinetics, what is the half life of nicotine in her body? d. The nicotine in the patch is abruptly exhausted after one day. How long will it take from that time for her blood concentration to decline to 5 g/liter? e. This smoker wishes to quit because she is newly pregnant. Her husband strongly advises her not to use a nicotine patch but to quit cold turkey (without such assistance) for the sake of the babys mental health. a nicotine patch but to quit cold turkey (without such assistance) for the sake of the babys mental health....
View Full Document
This note was uploaded on 03/27/2011 for the course ETX 103A taught by Professor Etx during the Winter '06 term at UC Davis.
- Winter '06