{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

2010 Bio 317 Lecture 5

# 2010 Bio 317 Lecture 5 - BIO 317 Lecture 5 Prof William...

This preview shows pages 1–3. Sign up to view the full content.

1 Prof. William Collins Office: 534 Life Sciences Building Office Hours: Mondays, 4:00 – 5:00 PM or by appointment Recommended Reading: Matthews, Chapter 7 BIO 317: Lecture 5 What Determines the Threshold Voltage for the Action Potential? g K E m E K ( ) g Na E m E Na ( ) = i K i Na When E m is at resting potential, K + and Na + currents are in balance. Assume that g K and g Na are not voltage dependent. What happens when E m is depolarized 15 mV from -70 mV to -55 mV? g K E m E K ( ) g Na E m E Na ( ) > i K i Na i K would increase in amplitude because the driving force would increase. i Na would decrease in amplitude because the driving force would decrease. Since i K > - i Na , K + current is the dominant influence and E m will repolarize to the resting potential, -70 mV.

This preview has intentionally blurred sections. Sign up to view the full version.

View Full Document
2 What Determines the Threshold Voltage for the Action Potential? Assume that g K and g Na ARE voltage dependent. What happens when E m is depolarized 15 mV from -70 mV to -55 mV? g K E m E K ( ) g Na E m E Na ( ) > ? < In reality, both g K and g Na are voltage dependent. Depolarization g Na (fast) and g K (slow).
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

### What students are saying

• As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

Kiran Temple University Fox School of Business ‘17, Course Hero Intern

• I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

Dana University of Pennsylvania ‘17, Course Hero Intern

• The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

Jill Tulane University ‘16, Course Hero Intern