2010 Bio 317 Lecture 20

2010 Bio 317 Lecture 20 - 11/15/10 What is the signaling...

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11/15/10 1 What is the signaling pathway for NGF? NGF uses a proto-oncoprotein pathway for neuronal survival and development
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11/15/10 2 -NGF +NGF or injection of Ras oncoprotein (mimic) ras NGF action requires Ras
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11/15/10 3 What is the receptor for NGF? Trk oncogene (tropomyosin receptor kinase)
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11/15/10 4 The Trk orphan receptor is expressed in neurons TrkA
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11/15/10 5 Why does an oncogene pathway mediate different effects in neurons? How does the NGF signaling pathway mediate a wide range of effects?
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This note was uploaded on 03/28/2011 for the course BIO 317 taught by Professor Simonhalegoua during the Fall '08 term at SUNY Stony Brook.

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2010 Bio 317 Lecture 20 - 11/15/10 What is the signaling...

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