Lecture 2 - BIO 311 DNA Structure and Function Molecular...

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BIO 311 DNA Structure and Function
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Molecular Genetics Hereditary information is contained in genes composed of DNA. The genetic information stored in the DNA is used to direct the synthesis of thousands of proteins that the cell requires. The work of the cell is carried out by many different types of molecules, primarily proteins. Some cancers and diseases may be caused by inheritance.
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What is the Structure of DNA? Max von Laue discovered X-ray crystallography in 1912 Biologist began to use this means to determine the structure of proteins In 1953, Rosalind Franklin and Maurice Wilkins obtained a sharp X-ray diffraction photograph of DNA Rosalind Franklin, 1948 Rosalind Franklin’s X-ray Diffraction Photograph of DNA, 1953
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Putting the Data Together Erwin Chargaff determined in 1950 that DNA had a one to one ratio of A to T and G to C. L. Pauling and RB Corey obtained the precise atomic measurement of the a-helix in 1951 Rosalind Franklin obtained the X-ray diffraction photograph in 1953. J. Watson and F. Crick made the first model of the DNA helix in 1953 http://www.sumanasinc.com/webcontent/anis amples/molecularbiology/DNA_structure.html
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This note was uploaded on 03/28/2011 for the course BIO 311 taught by Professor Staff during the Fall '08 term at SUNY Stony Brook.

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Lecture 2 - BIO 311 DNA Structure and Function Molecular...

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