2010 Bio 320 Question Bank E

2010 Bio 320 Question Bank E - BIO 320 - General Genetics...

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BIO 320 - General Genetics Question bank E 1 I. Population genetics 1. O blood type is due to homozygosity for the i allele at the ABO locus. In a population at Hardy-Weinberg equilibrium for this locus, 9% of people are type O. What is the frequency of the i allele in this population? A) 0.18 B) 0.09 C) 0.3 D) 0.81 E) 0.045 2. In a population at Hardy-Weinberg equilibrium for two alleles A and a at a single locus, the frequency of aa homozygotes in the population is 0.49. What is the frequency of the AA homozyotes? A) 0.51 B) 0.03 C) 0.42 D) 0.49 E) 0.09 3. In a population at Hardy-Weinberg equilibrium, the frequency of people affected by a recessive Mendelian condition is 1/1600. What is the proportion of heterozygotes in the population? A) 1/40 B) 1/1600 C) 39/1600 D) 78/1600 E) 39/40 4. In a population at Hardy-Weinberg equilibrium, there are two alleles of a particular gene, B and b . 9% of the individuals in the population are homozygous for the dominant allele, B . What percentage of the population is heterozygous for this gene? A) 16% B) 91% C) 21% D) 42% E) 82% 5. Two alleles of a gene, G and g , are at Hardy-Weinberg equilibrium in a population. The frequency of the recessive allele, g , is 0.60. What is the genotype frequency of homozygotes for the dominant allele ( GG )? A) 0.40 B) 0.64 C) 0.16 D) 0.48 E) 0.20 6. In a population at Hardy-Weinberg equilibrium for two alleles B and b at a single locus, the frequency of the recessive allele b is 20%. What is the frequency of individuals displaying the dominant phenotype for this gene/trait? A. 4% B. 32% C. 64% D. 80% E. 96% 7. A dominant and a recessive allele of a single locus are present at equal frequencies in a large population at Hardy-Weinberg equilibrium. The population is reduced in a single generation to less than 50 individuals, and stays at this size for many generations. What is the likely consequence of the smaller population size? A) One of the two alleles will be lost from the population - it could be either the dominant or the recessive allele. B) The dominant allele will be lost from the population. C) The recessive allele will be lost from the population. D) Both alleles will remain at the same frequencies as before. E) New alleles will arise in the population. 8. The psychologist Steven Pinker carries a mutation in one copy of the IKBKAP gene on chromosome 9 (NY Times, 1/7/09). People homozygous for this mutation develop Riley-Day syndrome, a severe nervous system disorder with an incidence of about 1 in 3,600 in people of Eastern European Jewish descent. If Dr. Pinker fathered a child with someone from this population, what is the approximate probability that his child would develop Riley-Day syndrome? Assume the population is at H-W equilibrium for the mutation. A 1/60
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2010 Bio 320 Question Bank E - BIO 320 - General Genetics...

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