This preview shows pages 1–2. Sign up to view the full content.
BIO 320  General Genetics
Question bank E
1
I. Population genetics
1.
O blood type is due to homozygosity for the
i
allele at the
ABO
locus.
In a population at HardyWeinberg
equilibrium for this locus, 9% of people are type O.
What is the frequency of the
i
allele in this population?
A) 0.18
B) 0.09
C)
0.3
D) 0.81
E)
0.045
2.
In a population at HardyWeinberg equilibrium for two alleles
A
and
a
at a single locus, the frequency of
aa
homozygotes in the population is 0.49.
What is the frequency of the
AA
homozyotes?
A) 0.51
B) 0.03
C) 0.42
D) 0.49
E) 0.09
3.
In a population at HardyWeinberg equilibrium, the frequency of people affected by a recessive Mendelian
condition is 1/1600.
What is the proportion of heterozygotes in the population?
A)
1/40
B)
1/1600
C)
39/1600
D)
78/1600
E)
39/40
4.
In a population at HardyWeinberg equilibrium, there are two alleles of a particular gene,
B
and
b
.
9% of the
individuals in the population are homozygous for the dominant allele,
B
.
What percentage of the population
is heterozygous for this gene?
A)
16%
B)
91%
C)
21%
D)
42%
E)
82%
5.
Two alleles of a gene,
G
and
g
, are at HardyWeinberg equilibrium in a population.
The frequency of the
recessive allele,
g
, is 0.60.
What is the genotype frequency of homozygotes for the dominant allele (
GG
)?
A)
0.40
B)
0.64
C)
0.16
D)
0.48
E)
0.20
6.
In a population at HardyWeinberg equilibrium for two alleles
B
and
b
at a single locus, the frequency of the
recessive allele
b
is 20%. What is the frequency of individuals displaying the dominant phenotype
for this
gene/trait?
A.
4%
B.
32%
C.
64%
D.
80%
E.
96%
7.
A dominant and a recessive allele of a single locus are present at equal frequencies in a large population at
HardyWeinberg equilibrium. The population is reduced in a single generation to less than 50 individuals,
and stays at this size for many generations.
What is the likely consequence of the smaller population size?
A)
One of the two alleles will be lost from the population  it could be either the dominant or the recessive allele.
B)
The dominant allele will be lost from the population.
C)
The recessive allele will be lost from the population.
D)
Both alleles will remain at the same frequencies as before.
E)
New alleles will arise in the population.
8.
The psychologist Steven Pinker carries a mutation in one copy of the IKBKAP gene on chromosome 9 (NY
Times, 1/7/09).
People homozygous for this mutation develop RileyDay syndrome, a severe nervous
system disorder with an incidence of about 1 in 3,600 in people of Eastern European Jewish descent.
If Dr.
Pinker fathered a child with someone from this population, what is the approximate
probability that his child
would develop RileyDay syndrome?
Assume the population is at HW equilibrium for the mutation.
A 1/60
This preview has intentionally blurred sections. Sign up to view the full version.
View Full Document
This is the end of the preview. Sign up
to
access the rest of the document.
 Spring '08
 N/A
 Genetics, Population Genetics

Click to edit the document details