2010 Bio 320 Midterm 2

2010 Bio 320 Midterm 2 - BIO320 - GENETICS SPRING 2010...

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BIO320 - GENETICS SPRING 2010 1 MIDTERM EXAM 2 2:20 - 3:40 pm, April 20, 2010 FORM CODE = 0 (Blue) Before starting: • PLEASE TURN OFF and put away cellphones, pagers, PDAs and any other electronic devices, except for calculators. • Fill in your NAME and ID number on your multi-choice form . • Fill in your NAME and ID number on the short answer sheet . (the last page of this exam). There are 20 multi-choice questions worth 4 points each, and two short answer questions worth 10 points each. • Select the single best answer to each multichoice question. • Fill in answers on the multichoice form with a #2 pencil. Answer the short answer questions on the same page as the questions. The exam will run from 2:20 until 3:40. This includes the time needed to fill in your name and ID and to transfer answers to the multichoice form. There is no time allowed for this after 3:40. • During the exam, a TA will ask to check your ID and sign you in. Your exam will not be credited unless your ID is checked . • Multichoice forms and short answer pages will be collected as soon as time is called at 3:40. Remove the short answer page from the rest of the exam (which you can keep), check that your name and ID are filled in on the multichoice form AND the short answer page , and hand in both pages. • If you finish before 3:40, hand in your answer sheets at the front of the room, and sign in if your ID has not already been checked. ... good luck . ..
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BIO320 MIDTERM 2 – SPRING 2010 BLUE – CODE 0 2
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BIO320 MIDTERM 2 – SPRING 2010 BLUE – CODE 0 3 1. Which of the following statements about human diseases that arise due to defects in mitochondrial DNA is FALSE ? A. Such diseases exhibit variable expressivity due to heteroplasmy. B. Such diseases are maternally inherited. C. Whether a pathogenic (disease) phenotype is observed depends on the energy requirement of the cell. D. A man who is heteroplasmic for a mitochondrial mutant that causes a particular disease has a 50% chance of transmitting the disease to his daughters. 2 . Which of the following cannot be used as a marker in constructing a linkage map? A. A restriction fragment length polymorphism (RFLP) site. B. A dominant mutation with a visible phenotype, in an unidentified gene. C. A microsatellite or short tandem repeat locus with polymorphic repeat numbers. D. A long, conserved open reading frame. E. A single nucleotide polymorphism (SNP). 3. T4 bacteriophage carrying two different mutant alleles of the rIIA gene, rIIA-3 and rIIA-9 were used to infect the permissive E. coli B strain. The resulting phage lysate was then used to infect both the E. coli B strain as well as the E. coli K strain. Only rIIA + phage can form plaques on the E. coli K strain. The number of plaques formed on the two different bacterial strains was counted: number of plaques on E. coli B strain 10,000 number of plaques on E. coli K strain 15 What is the map distance between the two mutations? A.
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This note was uploaded on 03/28/2011 for the course BIO 320 taught by Professor N/a during the Spring '08 term at SUNY Stony Brook.

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2010 Bio 320 Midterm 2 - BIO320 - GENETICS SPRING 2010...

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