Lecture 14 Introduction to Central Nervous System

Lecture 14 Introduction to Central Nervous System -...

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10/18/2010 1 Reading Assignment Chapter 6, pp. 138-143, 173-190 When you e-mail me ( [email protected] ), please provide your entire name and SBU ID# There will be no response if there is no SBU ID# provided E-mails should use correct English grammar and spelling E-mails should be professional and respectful in tone and content While in lecture, please turn off all cell phones Cellular Constituents of the Central Nervous System Neurons Glia (Neuroglia) Ependymal Cells
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10/18/2010 2 Release neurotransmitters Neuron Doctrine: Neurons are the Basic Signaling Units of the Nervous System • PN01011.JPG Variety of Nerve Cell Morphologies Found in the Human Nervous System
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10/18/2010 3 Diverse Neuron Structures Presage Function Receptor Endings Functional Organization of the Nervous System Connections: Chemical and Electrical Synapses
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10/18/2010 4 Inhibitory Excitatory Cellular Constituents of the Central Nervous System Neurons Glia (Neuroglia) Ependymal Cells
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10/18/2010 5 Types of Glia Ratio of Neuroglia to Neurons: ≈ 10:1 Types of Glia Maintain chemical environment Myelin formation Scavenger Blood-Brain Barrier (Schwann cells in PNS) (Related to Reuptake of neurotransmitters, K + macrophages)
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10/18/2010 6 Types of Glia Maintain chemical environment Myelin formation Scavenger Blood-Brain Barrier (Schwann cells in PNS) (Related to Reuptake of neurotransmitters macrophages)
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10/18/2010 7 Cellular Constituents of the Central Nervous System Neurons Glia Ependymal Cells Ependymal Cells
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10/18/2010 8 Ventricles of the Brain Formed by the choroid plexus: 500 ml / day Cerebrospinal Fluid
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10/18/2010 9 Ependymal Cell Specialization: Choroid Plexus- Manufacture and Secret CSF Formed by the choroid plexus: 500 ml / day Fills ventricles & subarachnoid space Cerebrospinal Fluid
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10/18/2010 10 Meninges Dense connective tissue Modified loose connective tissue Web-like membranous tissue Meninges Subdural hemorrhage Subarachnoid hemorrhage
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10/18/2010 11
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10/18/2010 12 Formed by the choroid plexus: 500 ml / day Fills ventricles & subarachnoid space CSF turns over ≈ 3-4 times a day Cerebrospinal Fluid Flow of CSF
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10/18/2010 13 Arachnoid Granulations Serve, ‘effectively’, as one-way valves for drainage of CSF into venous sinus Formed by the choroid plexus: 500 ml / day CSF (≈ 150 ml) turns over ≈ 3-4 times a day Fills ventricles & subarachnoid space Bathes the brain and empties into venous sinus Fluid pillow floats brain, reduces weight (buoyancy reduces weight ≈ 30 fold, from ≈ 1400 g to 50 g ), acts as a ‘shock absorber’ Chemically regulated environment different from blood: Lower levels of K + , Ca 2+ , HCO 3- and glucose Na + similar Elevated levels of H + (CSF: pH 7.33 vs.
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This note was uploaded on 03/28/2011 for the course BIO 328 taught by Professor Cabot during the Fall '07 term at SUNY Stony Brook.

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Lecture 14 Introduction to Central Nervous System -...

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