wk9 - Covel Peer Learning LS 4 (Rachel Care) Week 9 Week...

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Covel Peer Learning – LS 4 (Rachel Care) Week 9 Week 8/9 Material: I. Positional Cloning purpose: “RFLP” stands for: RFLPs are visualized by: 1. A rare recessive X-linked mutation, d, has been found which is caused by a point mutation (single nucleotide polymorphism) in exon 1 of the gene responsible for particularly bad dancing. The mutation happens to cause a RFLP such that EcoRI will not cut the mutant fragment. EcoRI normally cute to give two bands: 200 bp and 600 bp. Assume that unrelated individuals do not carry the mutation. Fill in genotypes for known individuals and possible genotypes for the unknowns: 1 2 3 4 5 6 7 8 9 Genotype (s) Draw the appropriate bands on the gel for each individual: Ladder 1 2 3 4 5 6 7 8 9 2. A witch has 9 children and wants to know which of them will grow up to
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develop magic powers. The ability to perform magic is caused by a dominant mutation in the boredom gene. The witch marries a wizard, but both are half-bloods (ie, each had one Muggle parent). The witch comes to UCLA seeking genetic counseling to see which of her 9 children are Squibs (are non-magical). You find a single nucleotide polymorphism
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This note was uploaded on 03/28/2011 for the course LS 4 taught by Professor Ribaya during the Spring '08 term at UCLA.

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wk9 - Covel Peer Learning LS 4 (Rachel Care) Week 9 Week...

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