2010_midterm_I_key

2010_midterm_I_key - Purdue ID: Biol 241 - Spring 2010...

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Purdue ID: Biol 241 - Spring 2010 Midterm I 2/15/2010 Question 1 (30 points) Question 2 (8 points) Question 3 (8 points) Question 4 (10 points) Question 5 (10 points) Question 6 (8 points) Question 7 (8 points) Question 8 (4 points) Question 9 (6 points) Question 10 (8 points) Total
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2010, Biol 241 Midterm I Purdue ID KEY Question 1, (Multiple-choice format, 2 points each) 1) Assuming that a G1 somatic cell nucleus in a M. pilosula female contains 8 picograms of DNA. How much DNA would be expected in a germ cell (after meiosis) produced by this female? A) 16 picograms B) 32 picograms C) 8 picograms D) 4 picograms 2) With complementation, a likely ratio resulting from a dihybrid cross would be: A) 9:3:4 B) 9:7 C) 12:3:1 D) 9:3:3:1 3) The percentage of individuals that show at least some degree of expression of a mutant genotype defines A) Expressivity B) Genetic suppression C) Penetrance D) Incoomplete dominance 4) A gain-of-function mutation that causes a mutant phenotype when heterozygous is called A) Dominant active B) Dominant negative C) Haplo-insufficient D) Dominant suppressor 5) An XXXY human will be: A) A male with 1 Barr bodies B) A female with 2 Barr bodies C) A male with 2 Barr bodies D) A male with 3 Barr bodies 2
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2010, Biol 241 Midterm I Purdue ID KEY Question 1 continued – 6) A conditional mutation is one that allows a mutant gene product to function normally under the ___ condition, but to function abnormally under the ___ condition. Such mutations are especially useful for the study of ___ mutations. A) Restrictive; permissive; dominant B) Permissive restrictive; dominant C) Dominant; recessive; semidominant D) Permissive; restrictive; lethal 7) A null allele is: A) A partial loss-of-function mutation B) A complete loss-of-function mutation C) A gain-of-function mutation D) Wild-type 8) Which of the following is responsible for the observation of semisterility? A) A crossover in the inverted region of a paracentric inversion B) A crossover in the inverted region of a pericentric inversion C) Adjacent segregation of reciprocal translocations D) The presence of a recessive lethal mutation on X chromosome 9) A virus is 10% adenine, 24% thymine, 30% guanine, and 36% cytosine. The genetic material in this virus is: A) Double-stranded DNA B) Single-stranded DNA C) Double-stranded RNA D) Single stranded RNA 10) What is the molecular basis for genetic anticipation? A) The methylation of cytosines at specific loci B) The expansion of tri-nucleotide repeats in certain genes C) The alteration of gene functions by specific point mutations D) The increase of gene copy number of duplications 3
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2010, Biol 241 Midterm I Purdue ID KEY 11) Consider the following reassociation kinectics curves, Which of the following statements is most likely incorrect A) The genome of A does not contain some highly repetitive DNA B) The genome of A is larger than the genome of B C) The genome of B contains mostly unique sequences D) The genome of B is larger than the genome of E. coli
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2010_midterm_I_key - Purdue ID: Biol 241 - Spring 2010...

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