Biol 241, Spring 2008 Midterm Exam I Purdue ID: ___________________ 1 Question 1. Please circle the correct answers (10 points total, 1 point each) 1) Assuming that a G1 somatic cell nucleus in M. pilosula female contains 8 picograms of DNA. How much DNA would be expected in a Metaphase I cell of a female? A) 16 picograms B) 32 picograms C) 8 picograms D) 4 picograms 2) With dominant epistasis, a likely ratio resulting from a dihybrid cross would be: A) 9:3:4 B) 9:7 C) 12:3:1 D) 9:3:3:1 3) Which of the following does NOT always occur with gene conversion: A) Formation of heteroduplex B) Mismatch repair C) Generation of recombinant chromosomes D) Formation of Holliday structure 4) In Drosophila, sex is determine by a balance between the number of haploid sets of autosome and the number of A) Centromeres B) Telomeres C) X chromosomes D) Y chromosomes 5) When an organism gains or loses one or more chromosomes but not a complete haploid set, the condition is known as A) Polyploidy B) Euploidy C) Aneuploidy D) Trisomy
Biol 241, Spring 2008 Midterm Exam I Purdue ID: ___________________ 2 6) Human patterned baldness is more prominent in males because it is a A) X-linked trait B) Y-linked trait C) Sex-influenced autosomal trait D) Conditional trait 7) The F factor that mediates the transferring of genetic materials during conjugation is a A) Bacteriophage B) Circular DNA C) Cell surface protein D) Single-Stranded RNA 8) The percentage of individuals that show at least some degree of expression of a mutant genotype defines A) Expressivity B) Genetic suppression C) Penetrance D) Incoomplete dominance 9) Which one of the following is Mendel’s First Law A) Unit factors in pairs. B) Dominance/Recessiveness C) Equal segregation D) Independent assortment 10) A loss-of-function mutation that causes a mutant phenotype when heterozygous is called A) Dominant active B) Dominant negative C) Haplo-insufficient D) Dominant suppressor
Biol 241, Spring 2008 Midterm Exam I Purdue ID: ___________________ 3 Question 2. (10 points) In unicorns, two unlinked autosomal loci interact to determine the type of tail. One locus controls whether a tail is present at all; the allele for a tail (T) is dominant over the allele for tailless (t). If a unicorn has a tail, then alleles at a second locus determine whether the tail is curly or straight. Farmer Baldridge has two unicorns with curly tails. When he crosses these two unicorns, ½ of the progeny have curly tails, ¼ have straight tails, and
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