Lect 7 BOL Lipids2 - Lipids 2 Lecture 7...

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Lipids 2 Lecture 7 Digestion/absorption of lipids Transport of lipids Cardio vascular disease Development Risk factors Prevention
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Some digestion of fat occurs in the stomach 1. Gastric lipase (lipase: breaks apart lipids) Activated by an acidic environment Acts on triglycerides containing short- & medium-chain fatty acids
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Fat absorption occurs primarily in the small intestine
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Bile helps in fat digestion and absorption Made in liver, stored in and secreted by gallbladder Greenish fluid containing minerals cholesterol (2/3 is what we make=endogenous, 1/3 dietary=exogenous) phospholipids (e.g. lecithin): aid in fat emulsification bile salts: derived from cholesterol; also aid in fat emulsification bile pigments
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Bile emulsifies lipids Enzymes can act only on emulsified lipids
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Fat digestion in lumen of small intestine Pancreatic Lipase hydrolyzes dietary fats form micelles diffuse into the cells of small Intestine
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Absorption of fatty acids a. Short - and medium-chain fatty acids (< 12 carbons) Are water-soluble Enter the portal vein to the liver b. Long -chain fatty acids Not water-soluble re-form into triglycerides in intestinal cells Converted into chylomicrons Enter the lymphatic system ALL fatty acids require adequate protein for transport
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for release into blood and lymph
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This note was uploaded on 03/30/2011 for the course NUTRI SCI 10 taught by Professor Amy during the Spring '08 term at University of California, Berkeley.

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Lect 7 BOL Lipids2 - Lipids 2 Lecture 7...

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