Genome 371 Lecture 2 - Genome 371 Lecture 2 1/26/11 4:15 PM...

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1/26/11 4:15 PM Genome 371 Lecture 2 Page 1 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Lecture 2 Chromosome segregation-1 4 Oct 2010 Lecture 02 handout (pdf) Subscribe to podcast: Slide 1 Slide 2 Slide 3 Remember that RNA polymerase uses promoter sequences to determine where to begin transcription. .. it does not use the start codon, that's just for translation. Since the start codon has to be within the mRNA, we know that the start codon has to be "downstream" of the promoter. Home Course mechanics Help hours Calendar Syllabus Lectures, Podcasts Quiz Sections Practice problems Exams GoPost Send email to class Useful links The Gradiator
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1/26/11 4:15 PM Genome 371 Lecture 2 Page 2 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Slide 4 Slide 5 Slide 6 Slide 7
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1/26/11 4:15 PM Genome 371 Lecture 2 Page 3 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Slide 8 Slide 9 Slide 10 Slide 11
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1/26/11 4:15 PM Genome 371 Lecture 2 Page 4 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Slide 12 Slide 13 Slide 14 Slide 15
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1/26/11 4:15 PM Genome 371 Lecture 2 Page 5 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Slide 16 Slide 17 The research article is here . A short article (in non-technical language) about the research is here . (You may need to be on-campus to have access to full text of these articles.) Slide 18 Slide 19
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Genome 371 Lecture 2 Page 6 of 13 http://courses.washington.edu/au371mkr/resources/lecture_notes/lecture_02.html Slide 20 Slide 21 Slide 22 Slide 23 Most attempts to identify a disease gene first "map" the gene, i.e., identify the general region of the genome within which the gene resides, and then search that region for likely "candidate genes". It would be more powerful and useful to identify precisely the gene and the bases that are mutated. .. but that technology is just starting to take off.
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Genome 371 Lecture 2 - Genome 371 Lecture 2 1/26/11 4:15 PM...

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