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Killian-Prions-55304 - BIO231 Genetics Lecture 14b Prions and Review I believe in compulsory cannibalism If people were forced to eat what they

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4/2/11 “I believe in compulsory cannibalism . If people were forced to eat what they killed, there would be no more wars.” Abbie Hoffman (American activist and writer. 1936-1989) BIO231 – Genetics Lecture 14b Prions and Review TCNJ Darrell Killian
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4/2/11 After synthesis, proteins must be folded into three-dimensional shape Chaperone proteins assist folding Misfolded proteins are tagged and dismantled Proteins can fold in more than one way Misfolded proteins can cause disease Protein Folding Lewis, Human Genetics , Chaperone Proteins: bind to unfolded polypeptide chains and promote proper protein folding (or unfolding)
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4/2/11 The 26S Proteasome Protein complex found in all Eukaryotes and Archaea, and some bacteria The major function of the Proteasome is as a protease. Proteins degraded by the proteasome: misfolded proteins proteins that are regulated proteins no longer needed cleaved proteins
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4/2/11 Misfolding of Protein Impairs Function Lewis, Human Genetics ,
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This note was uploaded on 04/02/2011 for the course GENETICS 8383 taught by Professor Love during the Spring '11 term at Rutgers.

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Killian-Prions-55304 - BIO231 Genetics Lecture 14b Prions and Review I believe in compulsory cannibalism If people were forced to eat what they

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