Ch2_Mendel_Fall_2010am - Chapter 2 - Mendels breakthrough:...

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1 Chapter 2 - Mendel’s breakthrough: patterns, particles, and principles of heredity 2.1 The historical puzzle of inheritance and how Mendel’s experimental approach helped solve it 2.2 Mendel’s approach to genetic analysis including his experiments and related analytic tools 2.3 Two comprehensive examples of Mendelian inheritance in humans GENE3200am - Bedell - Ch 2 - 8/17/2010
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2 Artificial selection has been an important practice since before recorded history Domestication and selective breeding of plants and animals 19 th century – precise techniques for controlled matings in plants and animals to produce desired traits in many offspring What was known about heredity before 1843, when Mendel started his studies? GENE3200am - Bedell - Ch 2 - 8/17/2010
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3 Black Sea Mediterranean Sea Persian Gulf Map of the Fertile Crescent with approx areas and dates of domestication of animals and plants ~ 12,000 years ago – Neolithic revolution, shift from hunter- gatherers to agriculture GENE3200am - Bedell - Ch 2 - 8/17/2010
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4 Domestication of corn from teosinte, a wild grass Occurred in southwest Mexico 6,000 – 10,000 yrs ago Artificial selection on four key traits; 2% - 4% of genome GENE3200am - Bedell - Ch 2 - 8/17/2010
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5 Example of artificial selection: All modern domestic dogs are descendants of the Gray Wolf GENE3200am - Bedell - Ch 2 - 8/17/2010
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6 Artificial selection has been an important practice since before recorded history Domestication and selective breeding of plants and animals 19 century – precise techniques for controlled matings in plants and animals to produce desired traits in many offspring What was known about heredity before 1843, when Mendel started his studies? Many biologists believed that offspring had a "blending" of parental traits But why would some traits disappear and then reappear in subsequent generations? Doberman coat color is a modern example GENE3200am - Bedell - Ch 2 - 8/17/2010
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7 What color of pups would occur from mating a red Dobie with a black Dobie? With these two adults, there were four colors of pups GENE3200am - Bedell - Ch 2 - 8/17/2010
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8 How could a mating of a red Dobie with a black Dobie produce a litter of pups with four different colors? Red X Black Black Blue Fawn Red GENE3200am - Bedell - Ch 2 - 8/17/2010
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9 Why would a different red female mated to the same black male produce pups of only two colors? Black male Red female - 1 All four colors X Red female - 2 X Only black and red X GENE3200am - Bedell - Ch 2 - 8/17/2010
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10 Why would different black females mated to the same black male have different colors of pups? Black male Black female - 1 X X Only black Black female - 2 All four colors GENE3200am - Bedell - Ch 2 - 8/17/2010
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11 Now it’s known there are two genes controlling these coat colors Using Mendel's laws, we can deduce the genotype of these parents and calculate the expected proportions of pups of each color Red ( bb Dd ) x Black ( Bb Dd ) Black (3/8 Bb D- ) Blue (1/8 Bb dd
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Ch2_Mendel_Fall_2010am - Chapter 2 - Mendels breakthrough:...

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