Lysosomes

Lysosomes - Lysosomes Click to edit Master subtitle style...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
Click to edit Master subtitle style Lysosomes Properties of lysosomes
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Click to edit Master subtitle style Properties of Lysosomes Acidic organelles (pH ~ 5) Proton pumps in membranes No fixed shape ; 0.05-0.5 μ m Acid phosphatase staining: EM Contain hydrolases Digest contents including lipids and macromolecules Biogenesis
Background image of page 2
Click to edit Master subtitle style Biogenesis of Lysosomes Re: default pathwys Page 779 Molecular Biology of the Cell (© Garland Science 2008)
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Protein Movement to Lysosomes Exiting the Default Pathway Soluble Lumenal Proteins Lysosomal Hydrolases Membrane proteins Man-6-P Receptor Lysosomal membrane proteins (LAMPS) Soluble prts: Man-6- P
Background image of page 4
Man-6- P Tag: Produced in Two Steps GlcNAc phosphotransferase reaction Uridine- P- P - GlcNAc Conversion BEYOND (Man)5GlcNAc)2 Leads to production of complex Or hybrid oligosaccharides. Addition of GlcNac-P can occur Multiply and on various intermediates Prior to OR INCLUDING Man5.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 14

Lysosomes - Lysosomes Click to edit Master subtitle style...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online