181lec7.key - Psych 181: Dr. Anagnostaras Lec 7:...

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Unformatted text preview: Psych 181: Dr. Anagnostaras Lec 7: Schizophrenia and Parkinson's Disease John Nash Incidence about 1 in 100 Schizophrenia Positive Symptoms Excesses, exaggerations, or distortions (+) Disorganized speech indicating a thought disorder (loose association to word salad) Hallucinations sensory experiences without external stimulation commonly auditory Delusions beliefs that are contrary to reality commonly persecutory in nature sometimes delusions of grandeur 1 2 3 Sunday, January 9, 2011 Schizophrenia Negative Symptoms Characterized by behavioral defcits () Avolition lack of energy & inability to persist in routine activities Alogia (poverty of speech) reduction in the amount or content of speech Anhedonia inability to experience pleasure Asociality severe impairment in social relationships Flat Affect or Incongruent Affect lack of or inappropriate emotional expression At least 2 of the following for 1 month: delusions hallucinations disorganized speech disorganized or catatonic behavior negative symptoms Marked functional impairment Continuous signs for 6 months Not due to drugs (e.g., amphetamine psychosis) DSM-IV Criteria Type I versus Type II 4 5 6 Sunday, January 9, 2011 An Array of Related Psychotic Disorders Three Subtypes of Schizophrenia (DSM-IV) Paranoid Type preoccupation with delusions and hallucinations no disorganized speech catatonia or flat affect Disorganized Type Disorganized speech, behavior, often inappropriate does not meet criteria for Catatonic Type Catatonic Type Clinical picture with at least two: motoric immobility, catalepsy, stupor (waxy inflexibility) excessive motor activity that is apparently purposeless extreme negativism or mutism peculiarities of movement (e.g., voluntary assumption of bizarre postures), stereotypies, odd mannerisms, or grimacing echolalia or echopraxia 7 8 9 Sunday, January 9, 2011 Hospitalized mental patients (x1000) Year 10 11 12 Sunday, January 9, 2011 15 13 14 15 Sunday, January 9, 2011 16 17 18 Sunday, January 9, 2011 19 20 21 Sunday, January 9, 2011 Increase in DA transmission exacerbates Schizophrenia...
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181lec7.key - Psych 181: Dr. Anagnostaras Lec 7:...

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