181lec10.key - Psych 181: Dr. Anagnostaras Lec 10:...

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Psych 181: Dr. Anagnostaras Lec 10: Marijuana Marijuana and cannabinoids Cannabis sativa , hemp One of earliest non-food plants cultivated Fber for rope, seeds for oil and birdseed 8000 BC 2700 BC 2000 BC 1000 AD 1850s 1996 1st archaeological evidence of hemp use Medical use in China Ritual use in India Hashish use in Arab world Westerm world Fnd bioactiv. Use semi- legal in CA/ AZ Wide Distribution 1 2 3 Sunday, January 9, 2011
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Marijuana and cannabinoids Cannabinoids pharmacologically active compounds over 60 (delta-9-tetrahydrocannabinol ( Δ 9- THC), Δ 8-THC, cannabinol, etc.) O CH2 CH2 Δ 9-Tetrahydrocannabinol OH CH3 H3C H3C CH2 CH3 CH2 Forms and preparations Marijuana mixture of leaves, stems, tops 1960 ʼ s: 1-3% THC; 1990 ʼ s: up to 8-10% “Bubble Gum” “Big Bud” “Dutch Northern Lights” Use in America 4 5 6 Sunday, January 9, 2011
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Forms and preparations Hashish dried resin from top of female plant THC usually 2-5%, but up to 15% Hash Oil organic extraction from hashish THC usually ~ 10-20% up to 70% Synthetic cannabinoids Developed for research Some very potent CH2 CH3 N WIN 55212 O C O N O History Second only to 7 8 9 Sunday, January 9, 2011
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History 1960 CA Laws Misdemeanors < 28.5 g (1 oz) Jail time: None Fine: $100 > 28.5 g 6 months $500 Gift < 28.5 None; $100 < 28.5 g at school 10 days
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181lec10.key - Psych 181: Dr. Anagnostaras Lec 10:...

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