ch369_3-7sp11_op2_notes

ch369_3-7sp11_op2_notes - Oxidative Phosphorylation Chapter...

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Unformatted text preview: Oxidative Phosphorylation - Chapter 15 Using the energy contained within reduced cofactors (NADH & QH 2 ) to make ATP. Oxidative phosphorylation (OP) occurs in the mitochondria (in eukaryotes). The overall reaction for oxidizing NADH is: The reaction is done in a series of small steps, using a series of spontaneous electron transfer (ET) reactions that release energy. Energy from ET chain pumps excess protons into intermembrane space. Then ATP uses the energy released by spontaneous H + transport to make ATP. ATP synthase uses the energy released by proton fow to make ATP. The energy released by spontaneous H + fow is used to create an environment where ATP is stabilized relative to ADP + P i ATP synthase Oxidative phosphorylation can make a lot of ATP. In total, about 32 to 36 ATPs by fully oxidizing one molecule of glucose. The process is not 100% efFcient; some energy that does not successfully make ATP is lost as heat. Study question #71 Study question #71 One problem that has not yet been addressed- How to get the NADH produced in glycolysis into the mitochondrial matrix, when it can’t cross the mitochondrial membrane ? How to get the NADH produced in glycolysis into the mitochondrial matrix, when it can’t cross the mitochondrial membrane ?...
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This note was uploaded on 04/02/2011 for the course CH 369 taught by Professor Kbrowning during the Spring '07 term at University of Texas.

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ch369_3-7sp11_op2_notes - Oxidative Phosphorylation Chapter...

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