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Lecture 15 10-25-10

Lecture 15 10-25-10 - Lecture 15 Lecture 15 Synapses...

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Unformatted text preview: Lecture 15 Lecture 15 Synapses Synapses Sensory Systems Sensory Systems 25 October 2010 25 October 2010 Neuromuscular Junction Simultaneous Na + and K + currents cause depolarization Neuromuscular Junction In Skeletal Muscle Nicotinic receptor – ionotropic; blocked by curare Types of cholinergic receptors In cardiac muscle, cholinergic receptors are muscarinic, which are metabotropic receptors. Muscarinic receptors are blocked by atropine. Neurotransmitters and Receptors in Vertebrate Central Nervous Systems Neuromuscular Junction vs. Central Nervous System Synapse Central Nervous System Synapse Due to low-voltage EPSPs and IPSPs at CNS synapses, the development of an action potential at the axon hillock requires carefully coordinated input to produce sufficient embrane depolarization to reach threshold. Synaptic Plasticity ynaptic function can change over time due to changes in 1) number of transmitter release sites, 2) probability of vesicular release of transmitter, and 3) number of molecules of released transmitter....
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Lecture 15 10-25-10 - Lecture 15 Lecture 15 Synapses...

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