Lecture 14 10-21-10

Lecture 14 10-21-10 - Neuromuscular Junction Neuromuscular...

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Lecture 14 Lecture 14 Membrane Potentials Membrane Potentials Synapses Synapses 21 October 2010 21 October 2010
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Action Potential
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Action Potential
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Propagation of Action Potential
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Propagation of Action Potential
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Propagation of Action Potential Absolute Refractory Period Relative Refractory Period
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Propagation of Action Potential
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Propagation of Action Potential Saltatory Propagation: Conduction velocity is faster in myelinated than in non-myelinated axons.
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Saltatory Propagation: Conduction velocity is faster in myelinated than in non- myelinated axons.
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Types of Synapses
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Electrical Synapses
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Chemical Synapses Voltage-gated calcium channels Synaptic transmission
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Chemical Synapses Ionotropic receptors Metabotropic receptors
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Post-Synaptic Potentials Excitatory Inhibitory
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Post-Synaptic Potentials Excitatory Inhibitory
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Post-Synaptic Potentials Excitatory Inhibitory
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Unformatted text preview: Neuromuscular Junction Neuromuscular Junction Neuromuscular Junction Neuromuscular Junction Cholinergic receptor Neuromuscular Junction Simultaneous Na + and K + currents cause depolarization Neuromuscular Junction In Skeletal Muscle Nicotinic receptor --blocked by curare Types of cholinergic receptors In cardiac muscle, cholinergic receptors are muscarinic, which are metabotropic receptors. Muscarinic receptors are blocked by atropine. Neuromuscular Junction vs. Central Nervous System Synapse Central Nervous System Synapse Central Nervous System Synapse Due to low-voltage EPSPs and IPSPs at CNS synapses, the development of an action potential at the axon hillock requires carefully coordinated input to produce sufficient membrane depolarization to reach threshold....
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Lecture 14 10-21-10 - Neuromuscular Junction Neuromuscular...

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